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Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology

The Iroquois homeobox (Irx) homeodomain transcription factors are important for several aspects of embryonic development. In the developing heart, individual Irx genes are important for certain postnatal cardiac functions, including cardiac repolarization (Irx5) and rapid ventricular conduction (Irx...

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Détails bibliographiques
Auteurs principaux: Gaborit, Nathalie, Sakuma, Rui, Wylie, John N., Kim, Kyoung-Han, Zhang, Shan-Shan, Hui, Chi-Chung, Bruneau, Benoit G.
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472592/
https://ncbi.nlm.nih.gov/pubmed/22992950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.081703
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