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GSPE interferes with tau aggregation in vivo: implication for treating tauopathy

Tauopathies are characterized by progressive neurodegeneration caused by intracellular accumulation of hyperphosphorylated tau protein aggregates in the brain. The present study was designed to test whether a grape seed polyphenolic extract (GSPE) previously shown to inhibit tau protein aggregation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Santa-Maria, Ismael, Diaz-Ruiz, Carmen, Ksiezak-Reding, Hanna, Chen, Alice, Ho, Lap, Wang, Jun, Pasinetti, Giulio Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472512/
https://ncbi.nlm.nih.gov/pubmed/22054871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.09.027
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