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Impact of hydroxyl radical-induced injury on calcium handling and myofilament sensitivity in isolated myocardium

Hydroxyl radicals (OH˙) are involved in the pathogenesis of reperfusion injury and are observed in acute heart failure, stroke, and myocardial infarction. Two different subcellular defects are involved in the pathogenesis of OH˙ injury, deranged calcium handling, and alterations of myofilament respo...

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Detalhes bibliográficos
Main Authors: Haizlip, Kaylan M., Hiranandani, Nitisha, Biesiadecki, Brandon J., Janssen, Paul M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472469/
https://ncbi.nlm.nih.gov/pubmed/22773772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01424.2011
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