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PU.1 binds to a distal regulatory element that is necessary for B-cell specific expression of the class II transactivator
The transcriptional coactivator CIITA regulates MHC class II genes. In the mouse, CIITA is expressed from three distinct promoters (pI, pIII, and pIV) in a developmental and cell type specific manner with pIII being responsible for B lymphocyte specific expression. Although the promoter proximal seq...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472449/ https://ncbi.nlm.nih.gov/pubmed/20363966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000079 |
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