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Palladium-catalyzed cross-coupling of aryl chlorides and triflates with sodium cyanate: A practical synthesis of unsymmetrical ureas

An efficient method for palladium-catalyzed cross-coupling of aryl chlorides and triflates with sodium cyanate is reported. The protocol allows for the synthesis of unsymmetrical N,N'-di- and N,N,N'-trisubstituted ureas in one pot, and is tolerant of a wide range of functional groups. Insi...

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Detalhes bibliográficos
Main Authors: Vinogradova, Ekaterina V., Fors, Brett P., Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472423/
https://ncbi.nlm.nih.gov/pubmed/22716197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja305212v
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