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Conservation and divergence between cytoplasmic and muscle-specific actin capping proteins: insights from the crystal structure of cytoplasmic Cap32/34 from Dictyostelium discoideum

BACKGROUND: Capping protein (CP), also known as CapZ in muscle cells and Cap32/34 in Dictyostelium discoideum, plays a major role in regulating actin filament dynamics. CP is a ubiquitously expressed heterodimer comprising an α- and β-subunit. It tightly binds to the fast growing end of actin filame...

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Hlavní autoři: Eckert, Christian, Goretzki, Agnieszka, Faberova, Maria, Kollmar, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472329/
https://ncbi.nlm.nih.gov/pubmed/22657106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-12-12
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