Complement activation is not required for obliterative airway disease induced by antibodies to MHC Class I: Implications for Chronic Lung Rejection

BACKGROUND: Role of non-complement activating antibodies (Abs) to mismatched donor HLA in pathogenesis of chronic lung rejection is not known. We utilized a murine model of obliterative airway disease (OAD) induced by Abs to MHC class I and serum from donor specific Abs (DSA) developed human lung tr...

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Detalhes bibliográficos
Main Authors: Takenaka, Masashi, Subramanian, Vijay, Tiriveedhi, Venkataswarup, Phelan, Donna, Hachem, Ramsey, Trulock, Elbert, Gelman, Andrew E, Patterson, G. Alexander, Hoshinaga, Kiyotaka, Mohanakumar, T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472127/
https://ncbi.nlm.nih.gov/pubmed/22980951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2012.08.011
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