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Identification of unknown protein function using metabolite cocktail screening
Proteins of unknown function comprise a significant fraction of sequenced genomes. Defining the roles of these proteins is vital to understanding cellular processes. Here, we describe a method to determine a protein function based on the identification of its natural ligand(s) by the crystallographi...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472112/ https://ncbi.nlm.nih.gov/pubmed/22940582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.07.016 |
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