Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers

Benzene exposure causes acute myeloid leukemia, and hematotoxicity, shown as suppression of mature blood and myeloid progenitor cell numbers. As the leukemia-related aneuploidies monosomy 7 and trisomy 8 previously had been detected in the mature peripheral blood cells of exposed workers, we hypothe...

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Hauptverfasser: Zhang, Luoping, Lan, Qing, Ji, Zhiying, Li, Guilan, Shen, Min, Vermeulen, Roel, Guo, Weihong, Hubbard, Alan E., McHale, Cliona M., Rappaport, Stephen M., Hayes, Richard B., Linet, Martha S., Yin, Songnian, Smith, Martyn T., Rothman, Nathaniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472034/
https://ncbi.nlm.nih.gov/pubmed/22643707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.143
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