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Monoclonal antibodies to the thyrotropin receptor: stimulating and blocking antibodies derived from the lymphocytes of patients with Graves disease.

Human monoclonal antibodies have been generated from heterohybridomas obtained by fusing mouse myeloma cells with peripheral lymphocytes from patients with active Graves disease. This report characterizes four antibodies as presumptive thyrotropin receptor antibodies because they specifically inhibi...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Valente, W A, Vitti, P, Yavin, Z, Yavin, E, Rotella, C M, Grollman, E F, Toccafondi, R S, Kohn, L D
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6292912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.21.6680
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