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Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines.

A 6-thioguanine-resistant, human lymphoblastoid B-cell line (GM1500 6TG A-11; IgG secreting) was mutagen-treated with low-level gamma-irradiation and selected for ouabain resistance. One line showing 10,000-fold higher drug resistance, designated KR-4, was fused with an Epstein-Barr virus-transforme...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kozbor, D, Lagarde, A E, Roder, J C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6292911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.21.6651
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