Berberine Inhibits Doxorubicin-Triggered Cardiomyocyte Apoptosis via Attenuating Mitochondrial Dysfunction and Increasing Bcl-2 Expression

Cardiomyocyte apoptosis is an important event in doxorubicin (DOX)-induced cardiac injury. The aim of the present study was to investigate the protection of berberine (Ber) against DOX- triggered cardiomyocyte apoptosis in neonatal rat cardiomyocytes and rats. In neonatal rat cardiomyocytes, Ber att...

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Detalhes bibliográficos
Main Authors: Lv, Xiuxiu, Yu, Xiaohui, Wang, Yiyang, Wang, Faqiang, Li, Hongmei, Wang, Yanping, Lu, Daxiang, Qi, Renbin, Wang, Huadong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471849/
https://ncbi.nlm.nih.gov/pubmed/23077597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047351
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