Soluble MOG35-55/I-A(b) Dimers Ameliorate Experimental Autoimmune Encephalomyelitis by Reducing Encephalitogenic T Cells

The MOG35-55 peptide-induced experimental autoimmune encephalomyelitis (EAE) model in C57BL/6 mice is a useful animal model to explore therapeutic approaches to T cell-mediated autoimmune diseases because the dominant T-cell epitope(s) have been defined. It is rational that antigen-specific immunosu...

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Main Authors: Gong, Yeli, Wang, Zhigang, Liang, Zhihui, Duan, Hongxia, Ouyang, Lichen, Yu, Qian, Xu, Zhe, Shen, Guanxin, Weng, Xiufang, Wu, Xiongwen
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471819/
https://ncbi.nlm.nih.gov/pubmed/23077616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047435
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