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Common Genetic Variants in miR-1206 (8q24.2) and miR-612 (11q13.3) Affect Biogenesis of Mature miRNA Forms

Cancer genome-wide association studies (GWAS) have identified many common genetic markers located in non-coding regions of the genome. Two notable examples are the multi-cancer susceptibility regions, 8q24.2 and 11q13.3. Since these GWAS signals localize to gene-poor regions, we investigated genetic...

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Bibliographic Details
Main Authors: Kim, Hye Kyung, Prokunina-Olsson, Ludmila, Chanock, Stephen J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471815/
https://ncbi.nlm.nih.gov/pubmed/23077621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047454
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