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Clathrin Pit-mediated Endocytosis of Neutrophil Elastase and Cathepsin G by Cancer Cells

Neutrophil elastase (NE) is a neutrophil-derived serine proteinase with broad substrate specificity. We have recently demonstrated that NE is capable of entering tumor cell endosomes and processing novel intracellular substrates. In the current study, we sought to determine the mechanism by which NE...

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Autori principali: Gregory, Alyssa D., Hale, Pamela, Perlmutter, David H., Houghton, A. McGarry
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471748/
https://ncbi.nlm.nih.gov/pubmed/22915586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385617
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