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Structural Basis for Malfunction in Complex II

Complex II couples oxidoreduction of succinate and fumarate at one active site with that of quinol/quinone at a second distinct active site over 40 Å away. This process links the Krebs cycle to oxidative phosphorylation and ATP synthesis. The pathogenic mutation or inhibition of human complex II or...

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書目詳細資料
Main Authors: Iverson, Tina M., Maklashina, Elena, Cecchini, Gary
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471735/
https://ncbi.nlm.nih.gov/pubmed/22904323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.408419
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