NHE3 Regulatory Factor 1 (NHERF1) Modulates Intestinal Sodium-dependent Phosphate Transporter (NaPi-2b) Expression in Apical Microvilli

P(i) uptake in the small intestine occurs predominantly through the NaPi-2b (SLC34a2) co-transporter. NaPi-2b is regulated by changes in dietary P(i) but the mechanisms underlying this regulation are largely undetermined. Sequence analyses show NaPi-2b has a PDZ binding motif at its C terminus. Immu...

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Bibliographische Detailangaben
Hauptverfasser: Giral, Hector, Cranston, DeeAnn, Lanzano, Luca, Caldas, Yupanqui, Sutherland, Eileen, Rachelson, Joanna, Dobrinskikh, Evgenia, Weinman, Edward J., Doctor, R. Brian, Gratton, Enrico, Levi, Moshe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Membrane Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471691/
https://ncbi.nlm.nih.gov/pubmed/22904329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.392415
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