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Targeted Therapeutic Strategies for the Management of Renal Cell Carcinoma

Agents targeting the VEGF and mTOR pathways remain the mainstay in the management of metastatic RCC. Understanding the importance of the VHL/HIF pathway in clear cell RCC has hitherto guided targeted therapy options in this disease, but other potential targets are beginning to emerge. Ongoing and fu...

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Autors principals: Singer, Eric A., Gupta, Gopal N., Srinivasan, Ramaprasad
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471654/
https://ncbi.nlm.nih.gov/pubmed/22343386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0b013e328351c646
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