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Menthol Activation of Corneal Cool Cells Induces TRPM8-Mediated Lacrimation but Not Nociceptive Responses in Rodents

PURPOSE. Stimulation to the cornea via noxious chemical and mechanical means evokes tearing, blinking, and pain. In contrast, mild cooling of the ocular surface has been reported to increase lacrimation via activation of corneal cool primary afferent neurons. The purpose of our study was to determin...

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Main Authors: Robbins, Ashlee, Kurose, Masayuki, Winterson, Barbara J., Meng, Ian D.
格式: Artigo
語言:Inglês
出版: The Association for Research in Vision and Ophthalmology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471555/
https://ncbi.nlm.nih.gov/pubmed/22952122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10025
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