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High levels of oxidized LDL in circulating immune complexes are associated with increased odds of developing abnormal albuminuria in Type 1 diabetes

BACKGROUND. Modified low-density lipoprotein (LDL) immune complexes (IC) have proinflammatory properties and play a role in albuminuria development. METHODS. We measured oxidized LDL (oxLDL) and advanced glycation end-product (AGE)–LDL in IC isolated from sera of Type 1 diabetic subjects followed fo...

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Autori principali: Lopes-Virella, Maria F., Carter, Rickey E., Baker, Nathaniel L., Lachin, John, Virella, Gabriel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471550/
https://ncbi.nlm.nih.gov/pubmed/21856760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfr454
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