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Somatostatin inhibits multireceptor stimulation of cyclic AMP formation and corticotropin secretion in mouse pituitary tumor cells.

The AtT-20/D16-16 mouse pituitary tumor cell secretes corticotropin (ACTH) in response to corticotropin-releasing factor (CRF), (-)-isoproterenol, and vasoactive intestinal peptide (VIP). These responses are associated with a rapid increase in cyclic AMP formation. Somatostatin (SRIF) markedly decre...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Heisler, S, Reisine, T D, Hook, V Y, Axelrod, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6128732/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.21.6502
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