Dynamics of Protein and its Hydration Water: Neutron Scattering Studies on Fully Deuterated GFP

We present a detailed analysis of the picosecond-to-nanosecond motions of green fluorescent protein (GFP) and its hydration water using neutron scattering spectroscopy and hydrogen/deuterium contrast. The analysis reveals that hydration water suppresses protein motions at lower temperatures (<∼20...

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Detalhes bibliográficos
Main Authors: Nickels, Jonathan D., O’Neill, Hugh, Hong, Liang, Tyagi, Madhusudan, Ehlers, Georg, Weiss, Kevin L., Zhang, Qiu, Yi, Zheng, Mamontov, Eugene, Smith, Jeremy C., Sokolov, Alexei P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471459/
https://ncbi.nlm.nih.gov/pubmed/23062349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.046
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