Determining the Mode of Action Involved in the Antimicrobial Activity of Synthetic Peptides: A Solid-State NMR and FTIR Study

We have previously shown that leucine to lysine substitution(s) in neutral synthetic crown ether containing 14-mer peptide affect the peptide structure and its ability to permeabilize bilayers. Depending on the substitution position, the peptides adopt mainly either a α-helical structure able to per...

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Detalhes bibliográficos
Main Authors: Lorin, Aurélien, Noël, Mathieu, Provencher, Marie-Ève, Turcotte, Vanessa, Cardinal, Sébastien, Lagüe, Patrick, Voyer, Normand, Auger, Michèle
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Membrane
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471444/
https://ncbi.nlm.nih.gov/pubmed/23062339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.055
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