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Molecular basis of lipid antigen presentation by CD1d and recognition by natural killer T cells

Together with peptides, T lymphocytes respond to hydrophobic molecules, mostly lipids, presented by the non-classical CD1 family (CD1a-e). These molecules have evolved complex and diverse binding grooves in order to survey different cellular compartments for self and exogenous antigens, which are th...

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Autors principals: Girardi, Enrico, Zajonc, Dirk M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471380/
https://ncbi.nlm.nih.gov/pubmed/23046129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2012.01166.x
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