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The Cross-Species A(3) Adenosine-Receptor Antagonist MRS 1292 Inhibits Adenosine-Triggered Human Nonpigmented Ciliary Epithelial Cell Fluid Release and Reduces Mouse Intraocular Pressure

PURPOSE: Antagonists to A(3) adenosine receptors (ARs) lower mouse intraocular pressure (IOP), but extension to humans is limited by species variability. We tested whether the specific A(3)AR antagonist MRS 1292, designed to cross species, mimicks the effects of other A(3)AR antagonists on cultured...

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Библиографические подробности
Главные авторы: Yang, Hui, Avila, Marcel Y., Peterson-Yantorno, Kim, Coca-Prados, Miguel, Stone, Richard A., Jacobson, Kenneth A., Civan, Mortimer M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471215/
https://ncbi.nlm.nih.gov/pubmed/16146920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02713680590953147
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