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Identification of human genomic clones coding the major histocompatibility antigens HLA-a2 and HLA-B7 by DNA-mediated gene transfer.

We have screened a large number of isolated human genomic clones that hybridize to a cloned HLA cDNA probe for their ability to direct the synthesis of HLA-A, -B, and -C surface antigens on mouse L cells following DNA-mediated gene transfer. The surface expression of human histocompatibility antigen...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Barbosa, J A, Kamarck, M E, Biro, P A, Weissman, S M, Ruddle, F H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6959120/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.20.6327
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