The simultaneous expression of both ephrin B3 receptor and E-cadherin in Barrett`s adenocarcinoma is associated with favorable clinical staging

BACKGROUND: In intestinal epithelium, tyrosine kinase receptor Ephrin B3 (Eph B3) maintains the architecture of the crypt-villus axis by repulsive interaction with its ligand ephrin-B1. While loss of Eph B3 is linked to colorectal cancer initiation, overexpression of Eph B3 in cancer cell lines inhi...

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Bibliographische Detailangaben
Hauptverfasser: Schauer, Matthias C, Stoecklein, Nikolas H, Theisen, Joerg, Kröpil, Feride, Baldus, Stephan, Hoelscher, Arnulf, Feith, Markus, Bölke, Edwin, Matuschek, Christiane, Budach, Wilfried, Knoefel, Wolfram Trudo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471084/
https://ncbi.nlm.nih.gov/pubmed/22583970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-783X-17-10
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