Controlling Self-Renewal and Differentiation of Stem Cells via Mechanical Cues

The control of stem cell response in vitro, including self-renewal and lineage commitment, has been proved to be directed by mechanical cues, even in the absence of biochemical stimuli. Through integrin-mediated focal adhesions, cells are able to anchor onto the underlying substrate, sense the surro...

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Bibliographic Details
Main Authors: Nava, Michele M., Raimondi, Manuela T., Pietrabissa, Riccardo
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471035/
https://ncbi.nlm.nih.gov/pubmed/23091358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/797410
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