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Identification of a cholesterol-regulated 53,000-dalton cytosolic protein in UT-1 cells and cloning of its cDNA.

UT-1 cells, a clone of Chinese hamster ovary (CHO) cells, have a 100- to 1,000-fold elevation in the amount of 3-hydroxy-3-methylglutaryl CoA reductase and therefore grow in the presence of compactin, an inhibitor of reductase. In this paper, we report that UT-1 cells also have a markedly increased...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Luskey, K L, Chin, D J, MacDonald, R J, Liscum, L, Goldstein, J L, Brown, M S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347089/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6959111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.20.6210
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