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A Type VI Secretion System Encoding Locus Is Required for Bordetella bronchiseptica Immunomodulation and Persistence In Vivo

Type VI Secretion Systems (T6SSs) have been identified in numerous Gram-negative pathogens, but the lack of a natural host infection model has limited analysis of T6SS contributions to infection and pathogenesis. Here, we describe disruption of a gene within locus encoding a putative T6SS in Bordete...

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Main Authors: Weyrich, Laura S., Rolin, Olivier Y., Muse, Sarah J., Park, Jihye, Spidale, Nicholas, Kennett, Mary J., Hester, Sara E., Chen, Chun, Dudley, Edward G., Harvill, Eric T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470547/
https://ncbi.nlm.nih.gov/pubmed/23071529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045892
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