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Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxy-icosatetraenoic acid.

Addition of arachidonic acid to suspensions of human blood leukocytes induces the synthesis of small amounts only of the C-5 lipoxygenase products as demonstrated by HPLC. However, the coincubation of blood platelets with the leukocytes always resulted in an activation of the C-5 lipoxygenase and fo...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Maclouf, J, de Laclos, B F, Borgeat, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347048/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6821131/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.19.6042
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