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Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin

Unlike many pathogens that are overtly toxic to their hosts, the primary virulence determinant of Mycobacterium tuberculosis appears to be its ability to persist for years or decades within humans in a clinically latent state. Since early in the 20th century latency has been linked to hypoxic condit...

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Detalhes bibliográficos
Main Authors: Sherman, David R., Voskuil, Martin, Schnappinger, Dirk, Liao, Reiling, Harrell, Maria I., Schoolnik, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34703/
https://ncbi.nlm.nih.gov/pubmed/11416222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121172498
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