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Platelet-derived growth factor binds specifically to receptors on vascular smooth muscle cells and the binding becomes nondissociable.

Radioiodinated platelet-derived growth factor (125I-PDGF) was used in studies of PDGF binding sites on vascular smooth muscle cells. There was an excellent correlation between the ability of 125I-PDGF to stimulate cell proliferation and to bind specifically to cultured vascular smooth muscle cells....

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Williams, L T, Tremble, P, Antoniades, H N
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6310551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.19.5867
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