Molecular cloning of mRNA sequences for cardiac alpha- and beta-form myosin heavy chains: expression in ventricles of normal, hypothyroid, and thyrotoxic rabbits.

We have isolated cDNA clones from thyrotoxic (pMHC alpha) and normal (pMHC beta) adult rabbit hearts. Restriction map analysis and DNA sequence analyses show that, although there is strong homology between overlapping regions of the two clones, they are distinctly different. The two clones exhibited...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sinha, A M, Umeda, P K, Kavinsky, C J, Rajamanickam, C, Hsu, H J, Jakovcic, S, Rabinowitz, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1982
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6193509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.19.5847
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