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The Seed Region of a Small RNA Drives the Controlled Destruction of the Target mRNA by the Endoribonuclease RNase E

Numerous small non-coding RNAs (sRNAs) in bacteria modulate rates of translation initiation and degradation of target mRNAs, which they recognize through base-pairing facilitated by the RNA chaperone Hfq. Recent evidence indicates that the ternary complex of Hfq, sRNA and mRNA guides endoribonucleas...

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Hlavní autoři: Bandyra, Katarzyna J., Said, Nelly, Pfeiffer, Verena, Górna, Maria W., Vogel, Jörg, Luisi, Ben F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469820/
https://ncbi.nlm.nih.gov/pubmed/22902561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.015
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