Excess protein O-GlcNAcylation and the progression of diabetic cardiomyopathy

We examined the role that enzymatic protein O-GlcNAcylation plays in the development of diabetic cardiomyopathy in a mouse model of Type 2 diabetes mellitus (DM2). Mice injected with low-dose streptozotocin and fed a high-fat diet developed mild hyperglycemia and obesity consistent with DM2. Studies...

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Main Authors: Fricovsky, Eduardo S., Suarez, Jorge, Ihm, Sang-Hyun, Scott, Brian T., Suarez-Ramirez, Jorge A., Banerjee, Indroneal, Torres-Gonzalez, Moises, Wang, Hong, Ellrott, Irina, Maya-Ramos, Lisandro, Villarreal, Francisco, Dillmann, Wolfgang H.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469670/
https://ncbi.nlm.nih.gov/pubmed/22874425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00548.2011
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