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Zoledronate Attenuates Angiogenic Effects of Angiotensin II-Stimulated Endothelial Progenitor Cells via RhoA and MAPK Signaling

BACKGROUND: New vessel formation plays a pivotal role in the pathogenesis of neovascular-related diseases. Endothelial progenitor cells (EPCs) were found to contribute to neovascular-related diseases and interference with EPC neovascularization may be a novel target for these diseases. Zoledronate (...

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Main Authors: Yang, Jin-Xiu, Chen, Bin, Pan, Yan-Yun, Han, Jie, Chen, Fei, Hu, Shen-Jiang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469623/
https://ncbi.nlm.nih.gov/pubmed/23071580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046511
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