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Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages

Alveolar macrophages (AMs) are exposed to frequent challenges from inhaled particulates and microbes and function as a first line of defense with a highly regulated immune response because of their unique biology as prototypic alternatively activated macrophages. Lung collectins, particularly surfac...

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Autors principals: Nguyen, Huy A., Rajaram, Murugesan V. S., Meyer, Douglas A., Schlesinger, Larry S.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469587/
https://ncbi.nlm.nih.gov/pubmed/22886503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00067.2012
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