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Inhibition of lung cancer cells growth, motility and induction of apoptosis by Klotho, a novel secreted Wnt antagonist, in a dose-dependent manner

Klotho (KL) is a transmembrane protein that can be shed, and act as a circulating hormone and modulate several signaling pathways. There also exists a splice variant of Klotho mRNA, which encodes a putative secreted protein (Klotho-S, KL-S) in both human and mouse. The potential anti-senescence gene...

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Bibliografske podrobnosti
Main Authors: Chen, Bo, Ma, Xiaoli, Liu, Shifeng, Zhao, Weihong, Wu, Jianqing
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469480/
https://ncbi.nlm.nih.gov/pubmed/22922788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21420
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