The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients

Tamoxifen is a standard therapeutical treatment in patients with estrogen receptor positive breast carcinoma. However, less than 50% of estrogen receptor positive breast cancers do not respond to tamoxifen treatment whereas 40% of tumors that initially respond to treatment develop resistance over ti...

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Bibliografische gegevens
Hoofdauteurs: Tanic, Nikola, Milovanovic, Zorka, Tanic, Nasta, Dzodic, Radan, Juranic, Zorica, Susnjar, Snezana, Plesinac-Karapandzic, Vesna, Tatic, Svetislav, Dramicanin, Tatjana, Davidovic, Radoslav, Dimitrijevic, Bogomir
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469474/
https://ncbi.nlm.nih.gov/pubmed/22892847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21346
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