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Side chain modified peptide nucleic acids (PNA) for knock-down of six3 in medaka embryos

BACKGROUND: Synthetic antisense molecules have an enormous potential for therapeutic applications in humans. The major aim of such strategies is to specifically interfere with gene function, thus modulating cellular pathways according to the therapeutic demands. Among the molecules which can block m...

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Detalhes bibliográficos
Main Authors: Dorn, Sebastian, Aghaallaei, Narges, Jung, Gerlinde, Bajoghli, Baubak, Werner, Birgit, Bock, Holger, Lindhorst, Thomas, Czerny, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469332/
https://ncbi.nlm.nih.gov/pubmed/22901024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-50
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