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Side chain modified peptide nucleic acids (PNA) for knock-down of six3 in medaka embryos

BACKGROUND: Synthetic antisense molecules have an enormous potential for therapeutic applications in humans. The major aim of such strategies is to specifically interfere with gene function, thus modulating cellular pathways according to the therapeutic demands. Among the molecules which can block m...

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Bibliografiske detaljer
Main Authors: Dorn, Sebastian, Aghaallaei, Narges, Jung, Gerlinde, Bajoghli, Baubak, Werner, Birgit, Bock, Holger, Lindhorst, Thomas, Czerny, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469332/
https://ncbi.nlm.nih.gov/pubmed/22901024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-50
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