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Isolation and identification of a biologically active peptide derived from the CH3 domain of human IgG1.

A 24-amino acid residue peptide has been isolated from the Fc region of a human IgG1 myeloma protein. The peptide has associated with it the same ability to induce murine B cells to polyclonally secrete antibody as does the intact Fc fragment. Amino acid composition of the peptide indicates that on...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Morgan, E L, Hugli, T E, Weigle, W O
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1982
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346902/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6215650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.17.5388
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