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Inhibition of Leishmania major PTR1 Gene Expression by Antisense in Escherichia coli

BACKGROUND: Protozoa related to Trypanosome family including Leishmania, synthesize enzymes to escape from drug therapy. One of them is PTR1 that its enzymatic activity is similar to dihydrofolate reductase (DHFR). Dihydrofolate reductase - thymidylate synthase has a major role in DNA synthesis, if...

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Bibliografische gegevens
Hoofdauteurs: Kheirandish, F, Bandehpour, M, Haghighi, A, Mahboudi, F, Mohebali, M, Kazemi, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Tehran University of Medical Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468993/
https://ncbi.nlm.nih.gov/pubmed/23113195
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