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Selective Constraint on Human Pre-mRNA Splicing by Protein Structural Properties

Alternative splicing (AS) is a major mechanism of increasing proteome diversity in complex organisms. Different AS transcript isoforms may be translated into peptide sequences of significantly different lengths and amino acid compositions. One important question, then, is how AS is constrained by pr...

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Detalhes bibliográficos
Main Authors: Gelly, Jean-Christophe, Lin, Hsuan-Yu, de Brevern, Alexandre G., Chuang, Trees-Juen, Chen, Feng-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468958/
https://ncbi.nlm.nih.gov/pubmed/22936073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evs071
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