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MCP1/CCR2 Axis Promotes Vein Graft Neointimal Hyperplasia through Its Signaling in Graft Extrinsic Cell Populations

OBJECTIVE: To evaluate direct versus indirect MCP-1/CCR2 signaling and identify the cellular producers and effectors for MCP-1 during neointimal hyperplasia (NIH) development in vein grafts (VG). METHODS AND RESULTS: Genomic analysis revealed an over-representation of 13 inflammatory pathways in WT...

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Detalhes bibliográficos
Main Authors: Fu, Chunhua, Yu, Peng, Tao, Ming, Gupta, Tushar, Moldawer, Lyle L., Berceli, Scott A., Jiang, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468948/
https://ncbi.nlm.nih.gov/pubmed/22904274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.255786
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