Human Liver Stem Cell-Derived Microvesicles Inhibit Hepatoma Growth in SCID Mice by Delivering Antitumor MicroRNAs

Microvesicles (MVs) play a pivotal role in cell-to-cell communication. Recent studies demonstrated that MVs may transfer genetic information between cells. Here, we show that MVs derived from human adult liver stem cells (HLSC) may reprogram in vitro HepG2 hepatoma and primary hepatocellular carcino...

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Detalhes bibliográficos
Main Authors: Fonsato, Valentina, Collino, Federica, Herrera, Maria Beatriz, Cavallari, Claudia, Deregibus, Maria Chiara, Cisterna, Barbara, Bruno, Stefania, Romagnoli, Renato, Salizzoni, Mauro, Tetta, Ciro, Camussi, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Tissue-Specific Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468738/
https://ncbi.nlm.nih.gov/pubmed/22736596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1161
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