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Normal and neoplastic urothelial stem cells: getting to the root of the problem

Most epithelial tissues contain self-renewing stem cells that mature into downstream progenies with increasingly limited differentiation potential. It is not surprising that cancers arising from such hierarchically organized epithelial tissues retain features of cellular differentiation. Accumulatin...

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Bibliographic Details
Main Authors: Ho, Philip Levy, Kurtova, Antonina, Chan, Keith Syson
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468664/
https://ncbi.nlm.nih.gov/pubmed/22890301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrurol.2012.142
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