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Increased T Regulatory Cells Are Associated with Adverse Clinical Features and Predict Progression in Multiple Myeloma

BACKGROUND: Regulatory T (Treg) cells play an important role in the maintenance of immune system homeostasis. Multiple myeloma (MM) is a plasma cell disorder frequently associated with impaired immune cell numbers and functions. METHODS: We analyzed Treg cells in peripheral blood (n = 207) and bone...

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Detalhes bibliográficos
Main Authors: Muthu Raja, Karthick Raja, Rihova, Lucie, Zahradova, Lenka, Klincova, Maria, Penka, Miroslav, Hajek, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468567/
https://ncbi.nlm.nih.gov/pubmed/23071717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047077
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