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Chronic use of chloroquine disrupts the urine concentration mechanism by lowering cAMP levels in the inner medulla

Chloroquine, a widely used anti-malaria drug, has gained popularity for the treatment of rheumatoid arthritis, systemic lupus erythematosus (SLE), and human immunodeficiency virus (HIV). Unfortunately, chloroquine may also negatively impact renal function for patients whose fluid and electrolyte hom...

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Detalhes bibliográficos
Main Authors: von Bergen, Tobias N., Blount, Mitsi A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468520/
https://ncbi.nlm.nih.gov/pubmed/22791344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00547.2011
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