Flow-induced prostaglandin E(2) release regulates Na and K transport in the collecting duct

Fluid shear stress (FSS) is a critical regulator of cation transport in the collecting duct (CD). High-dietary sodium (Na) consumption increases urine flow, Na excretion, and prostaglandin E(2) (PGE(2)) excretion. We hypothesize that increases in FSS elicited by increasing tubular flow rate induce t...

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Hauptverfasser: Flores, Daniel, Liu, Yu, Liu, Wen, Satlin, Lisa M., Rohatgi, Rajeev
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468495/
https://ncbi.nlm.nih.gov/pubmed/22696602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00169.2012
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